Protein Modification Reagents
Medchemexpress LLC L-dithiothreitol | 16096-97-2 | MFCD00064305 | 98.0% | 154.25 g·mol⁻¹ | C4H10O2S2 | 10 MG
L-dithiothreitol (DTT) is a small-molecule thiol reducing agent used to cleave disulfide bonds and maintain cysteine residues in the reduced state during biochemical and molecular biology workflows. It is commonly used in sample preparation, protein analysis, and enzymatic assays.
- Effective reducing agent for cleaving disulfide bonds.
- Helps maintain proteins in a reduced, active state.
- Soluble in water and compatible with common buffers.
- High purity suitable for biochemical applications.
- Available in small quantities for analytical and research use.
Medchemexpress LLC Carboxyethyl-γ-aminobutyric acid | 4386-03-2 | MFCD00057954 | 175.18 g/mol | C7H13NO4 | 10 MG
Carboxyethyl-γ-aminobutyric acid is a small-molecule biochemical reagent supplied as a powder for laboratory research. Identified by CAS 4386-03-2, it has formula C7H13NO4 and molecular weight 175.18 g/mol. Store and handle according to the safety data sheet and product documentation.
AG Scientific Inc Dithiothreitol, DTT, 100 G
Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.CAS Number: 3483-12-3Molecular Weight: 154.2Chemical Formula: C4H10O2S2Solubility: 10% solution in water. Clear and colorlessStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC DSPE-PEG-folate | 90.0% | 2000 g/mol (average) | C63H104N9O15P | 10 MG
DSPE-PEG-Folate is a PEGylated phospholipid supplied as a powder that presents folic acid as a targeting ligand for folate receptor-mediated delivery. It self-assembles into micelles or lipid bilayers and is intended for use in liposome formulation and targeted drug delivery research.
- Average molecular weight ~2000 g/mol.
- Purity 90.0%.
- Powder; light yellow to yellow.
- Soluble in DMSO at 50 mg/mL (requires ultrasonic).
- Storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Forms micelles and lipid bilayers for receptor-targeted delivery.
Cayman Chemical dPE-PEG 2000-CoH 5mg
A PEGylated derivative of DSPE; has been used to link transferrin receptors to the surface of liposomes encapsulating doxorubicin for targeted delivery of doxorubicin in vitro and in vivo; nanomicelles containing DSPE-PEG(2000)-COOH linked to borneol and encapsulating doxorubicin reduce tumor growth and metastasis in an in situ C6 murine model of glioblastoma
Cayman Chemical TrImethoprIm-PEG-amIntrIfl 1mg
A conjugated form of trimethoprim linked with polyethylene glycol (PEG) amine
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 | C19H22N2O8 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203957.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 | C19H22N2O8 | 250 MG
Ald-Ph-amido-PEG2-C2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker designed for antibody-drug conjugation (ADC). It features an activated N-hydroxysuccinimide (NHS) ester for amine coupling and a para-formylbenzoyl aldehyde for conjugation chemistry. The product is supplied as a colorless to light-yellow liquid with high purity and is intended for research use.
- Noncleavable two-unit PEG linker suitable for ADC construction.
- NHS ester for efficient amine coupling.
- Aldehyde (formyl) functional group for site-specific conjugation.
- High purity (approximately 98.5%).
- Liquid, colorless to light yellow appearance.
- Molecular weight 406.39 and formula C19H22N2O8.
- Storage: pure form -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
![eMolecules Broadpharm / Diazo Biotin-PEG3-DBCO / 5mg / 510428471 / BP-22452 / 95.000 / / [null] / 973.160 / C52H60N8O9S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502512619.JPG-250.jpg)
eMolecules Broadpharm / Diazo Biotin-PEG3-DBCO / 5mg / 510428471 / BP-22452 / 95.000 / / [null] / 973.160 / C52H60N8O9S
Broadpharm / Diazo Biotin-PEG3-DBCO / 5mg / 510428471 / BP-22452 / 95.000 / / [null] / 973.160 / C52H60N8O9S
eMolecules N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester | 2112732-03-1 | MFCD30723211 | 500mg
Broadpharm | N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester | 500mg | 343283639 | BP-23597 | 98.000 | 2112732-03-1 | MFCD30723211 | 578.704 | C26H50N4O10
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Medchemexpress LLC Biotin-PEG2-Mal | 305372-39-8 | 99.6% | 525.62 | 100 MG
Biotin-PEG2-Mal is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTAC.
Cayman Chemical AzIdo-dPEG7-amIn 25mg
A heterobifunctional PEGylated linker; contains a reactive NH2 end group, as well as an azide functional group for use in click chemistry reactions; has been used as a linker in the synthesis of bivalent mTOR inhibitors
eMolecules NH-bis(PEG1-azide) | 2100306-81-6 | MFCD30730376 | 500mg
Broadpharm | NH-bis(PEG1-azide) | 500mg | 347153848 | BP-23618 | 98.000 | 2100306-81-6 | MFCD30730376 | 243.271 | C8H17N7O2
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eMolecules Mal-amido-PEG9-amine TFA salt | 2182602-22-6 | | 500mg
Broadpharm | Mal-amido-PEG9-amine TFA salt | 500mg | 368397735 | BP-23834 | 98.000 | 2182602-22-6 | | 607.698 | C27H49N3O12
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Medchemexpress LLC Tco-peg4-vc-pab-mmae | 2758671-45-1 | 99.3% | 1522.91 | C78H127N11O19 | 1 MG
TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate used in antibody-drug conjugate (ADC) research and click-chemistry applications; it couples a trans-cyclooctene (TCO) reactive handle to a PEG4-spaced valine-citrulline-para-aminobenzyl (Val-Cit-PAB) cleavable linker and the cytotoxic payload MMAE.
- High purity (99.3%).
- Molecular weight 1522.91 g/mol.
- Chemical formula C78H127N11O19.
- CAS number 2758671-45-1.
- Suitable for iEDDA click chemistry with tetrazine reagents.
- Intended for ADC synthesis and conjugation research.
- Store at -20°C and protect from light; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
- Available in small research pack sizes (e.g., 1 MG).
eMolecules Mal-amido-PEG2-Val-Cit-PAB-OH | | | 100mg
Broadpharm | Mal-amido-PEG2-Val-Cit-PAB-OH | 100mg | 462125386 | BP-24348 | 98.000 | | | 689.767 | C32H47N7O10
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